ABSTRACT
Background: On March 12, 2020, WHO declared Novel Coronavirus disease as a pandemic outbreak all over the world. The outbreak had led the medical sector to a new platform, in the implementation of ancient knowledge of the Siddha medicine in treatment, management, and prevention of this prevailing pandemic. According to Siddha science, any vitiation in the life force is the main cause of diseases in human beings. pandemic diseases caused due to infectious microorganisms are called 'Kona' Noigal' in various Siddha literatures. Aim and objective: To classify the Novel Coronavirus disease based on the Siddha Humoural principles and to elicit the changes of Ninety-six Thatthuvam (Ninety - six basic principles), Uyir Thathukkal and Udal Thathukkal. Materials and methods: This study is accomplished mainly for literature research. Various Siddha texts such as Sattamuni gnanam, Agathiyar Gunavagadam, Agathiyar vallathi Naadi, Theraiyar Sekarappa, etc. were referred. Numerous research articles on COVID 19 were critically reviewed from Scopus, PubMed, Google Scholar, etc. Discussion: By critically reviewing the signs and symptoms of COVID-19 with Siddha science, the authors had thrown light especially on the involvement of all basic components of the Tri thodam particularly Mukkutram verupadu (Tri humoral vitiation) in eliciting the pathogenesis of the disease. Conclusion: In this scientific review, the authors have attempted to comprehend the pathogenesis of Novel coronavirus disease in the context of Siddha's basic principles.